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Here we report that AAV2-2 transduces CSMN with high efficiency upon direct cortex injection and that transduction efficiencies are similar during presymptomatic and symptomatic stages in h SOD1 CSMN transduction, the highest percentage reported to date.

Optogenetic stimulation of these fibers resulted in rapid inhibition of orexin neurons.

These observations suggest direct connectivity between POA GABAergic neurons and orexin neurons.

Language education refers to the process and practice of acquiring a second or foreign language.

It primarily is a branch of applied linguistics, however can be considered an interdisciplinary field.